Compiling and programming are successful, but program does not run at all

Hello all,

I am a electronic developer. Now i have a problem. I am using uvision 5 and ST link for SW development, debugging and programming.

the program can be successfully compiled, and to Flash in target programming. But the program does not run at all, either after programming or power off and on.

But the program can be run in debugging session without any problems, all desired functionalities are realized. I have no idea what the problem is.

Could you please help me?

thank you very much in advance

Ying