Keil-arm is not responding

I use pac25140 (arm cortex M4+) for my project. When I add a while(1) loop and start debug. The program is in while loop after that  Keil-arm is not responding.

int main(void)
{
// Disable global interrupts
__disable_irq();

board_init();
__disable_irq();
while(1){;}
}